Aldehyde Dehydrogenase: Cancer and Stem Cells
نویسندگان
چکیده
Aldehyde dehydrogenases (ALDH) belong to the oxidoreductase family, which catalyze the conversion of aldehydes to their corresponding acids. As a group of NAD(P)+-dependent enzymes, aldehyde dehydrogenases (ALDHs) are involved in oxidation of a large number of aldehydes into their weak carboxylic acids (Moreb, et al., 2012). ALDH is found in every subcellular region such as cytosol, endoplasmic reticulum, mitochondria, and the nucleus, with some even found in more than one location (Marchitti, et al., 2008).
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